During Dr. Holly Humphrey’s undergraduate and graduate medical education, the inpatient clinical learning environment was characterized by high-performing, interprofessional, collaborative team practice, including bedside patient care rounds, twice weekly interprofessional team conferences, and stable team memberships in inpatient, office-based, and intensive care unit settings. These characteristics fostered durable relationships, outstanding educational experiences, and high-quality patient care. Over time, systems forces undermined this standard for education and clinical practice. As President of the Josiah Macy Jr. Foundation, Dr. Humphrey initiated a 10-year strategic plan centered on supporting exemplary clinical learning environments, characterized by collaboration, belonging, and trust. Building on the prior decade of investment in interprofessional education, the Macy Foundation now aims to instill interprofessional collaboration in the clinical environment to ensure that future health professionals are both learning from and in high-performing interprofessional teams.